Breaking Into the MSL Role – Tips for Transitioning from Academia or Clinical Practice

Breaking Into the MSL Role – Tips for Transitioning from Academia or Clinical Practice

Introduction: Thinking of making the leap from academia or clinical practice to a Medical Science Liaison (MSL) role? You're not alone. Many successful MSLs started as PhDs, PharmDs, MDs, or healthcare professionals with no prior industry experience. The good news? It’s absolutely possible to make the transition — with the right strategy. In this post, we’ll cover practical tips to help you break into the MSL role, even if you’ve never worked in pharma.

1. Highlight Your Transferable Skills

Just because you haven’t been an MSL doesn’t mean you don’t have relevant experience. Think about your ability to:

  • Analyze and interpret complex scientific data
  • Present findings at conferences or meetings
  • Communicate across departments or disciplines
  • Educate patients, students, or colleagues

Whether you’ve been in the lab or at the bedside, these are the same skills that will help you succeed as an MSL.

2. Learn the Industry Landscape

Familiarize yourself with how pharmaceutical companies operate, the drug development process, and the role of Medical Affairs. Consider completing a short course or certification in medical affairs or clinical research. Understanding the business side of science will help you speak the language during interviews.

3. Build a Strategic Resume

Your academic CV won’t cut it in industry. Create a concise, achievement-focused resume tailored to MSL roles. Focus on:

  • Scientific expertise
  • Communication and presentation experience
  • Any exposure to clinical trials or real-world evidence

Include key terms like “KOL engagement,” “therapeutic area knowledge,” and “scientific exchange” to get past applicant tracking systems.

4. Grow Your Network

Many MSL jobs are landed through networking. Connect with current MSLs on LinkedIn, attend Medical Affairs webinars, and join MSL-focused groups. Don’t hesitate to reach out with a message like:

“Hi [Name], I’m a PhD in oncology exploring the MSL career path. I’d love to hear about your transition and any advice you’d be willing to share.”

These conversations can lead to mentorship, referrals, and insider insights.

5. Prepare for the Interview

MSL interviews are often multi-step and may include a scientific presentation or role-play scenario. Be ready to explain:

  • Why you want to transition into an MSL role
  • How your background makes you a great fit
  • How you’d build relationships with KOLs

Practice answering common questions and learn to speak with confidence about your scientific and interpersonal strengths.

6. Stay Persistent

Breaking in can take time, especially if you’re transitioning from a non-industry background. Don’t get discouraged. Every application, every networking conversation, and every interview gets you closer. Some candidates also take entry-level roles in medical communications, medical information, or clinical research to get their foot in the door — then pivot into an MSL role later.

Conclusion

Breaking into the MSL role without industry experience is a challenge — but absolutely achievable. By positioning your transferable skills, learning the landscape, networking strategically, and preparing thoroughly, you can overcome the experience gap and land your first MSL role.

Need help with your transition? Download The MSL Blueprint eBook for step-by-step guidance, proven strategies, and templates to help you break into medical affairs with confidence.