Top 10 MSL Interview Questions and How to Ace Them

Top 10 MSL Interview Questions and How to Ace Them

Introduction: You scored an interview for a Medical Science Liaison position – congratulations! This is a huge step toward landing your dream MSL job. Now, how do you prepare to knock it out of the park? The MSL interview process can be rigorous. Employers want to ensure you have the scientific expertise and the soft skills to excel in this unique role. The good news is that many MSL interview questions are predictable, and preparing for them will boost your confidence. In this post, we’ll go over the top 10 MSL interview questions and how to answer them with clarity and impact.

1. Tell me about yourself and why you want to be an MSL.

This is your chance to introduce your background and connect your experience to the MSL role. Focus on your scientific training, communication strengths, and passion for the field. End with a strong reason why this career excites you.

2. Why do you want to work for our company?

Research the company’s products, pipeline, and values. Show that you’re aligned with their mission and genuinely interested in contributing to their medical strategy. Tailor your response to their therapeutic area.

3. What clinical or research experience do you have that will help you in this MSL role?

Highlight any experience where you gained subject matter expertise, presented findings, or worked with clinicians. Emphasize your ability to digest and discuss complex data and apply it in real-world scenarios.

4. How do you stay up-to-date with the latest medical research and trends?

Demonstrate your habits for ongoing learning—reading journals, attending conferences, setting alerts, or joining professional networks. This shows initiative and scientific curiosity.

5. Describe a time you had to explain complex scientific information to a non-expert.

Use the STAR method to tell a clear story. Emphasize clarity, empathy, and tailoring your message to the audience. These are core MSL communication skills.

6. How would you approach building relationships with Key Opinion Leaders (KOLs)?

Talk about being proactive, respectful, and consistent. Mention researching each KOL, offering value, listening actively, and following through to build trust and credibility over time.

7. Give an example of how you handled a difficult question or skepticism about data.

Choose an example where you responded professionally and factually. Emphasize your ability to remain calm, rely on evidence, and seek internal support if needed. Scientific credibility and trust are key.

8. What would your plan be for your first 30/60/90 days in this MSL role?

Outline how you would approach onboarding, building knowledge, engaging KOLs, and contributing to the team. This shows initiative and understanding of the role’s priorities.

9. Why are you leaving your current position to pursue an MSL role?

Frame your response positively. Focus on what draws you to the MSL role—science, communication, field-based impact—and how your background makes you ready to contribute in a new capacity.

10. Do you have any questions for us?

Always come prepared with thoughtful questions. Ask about team structure, success metrics, onboarding, or the company’s future medical strategy. It shows engagement and preparation.

Bonus Tips for Interview Success

  • Use the STAR method (Situation, Task, Action, Result) for behavioral questions.
  • Showcase both your scientific and interpersonal strengths.
  • Practice clear, confident communication—especially about your research or clinical experience.
  • Be ready to give a scientific presentation or role-play scenario if asked.
  • Express enthusiasm for the company, the role, and their mission in healthcare.

Conclusion

Preparing for an MSL interview is all about connecting your background to the responsibilities of the role and demonstrating your communication and scientific strengths. Practice your answers, do your research, and show genuine excitement for the opportunity. With the right preparation and mindset, you can confidently step into the interview and prove that you're the MSL they've been looking for.

Need more help getting interview-ready? Check out The MSL Blueprint eBook for sample answers, resume tips, and bonus insights to help you land your first MSL job.